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The Bioperl Project is an international association of developers of open source Perl tools for bioinformatics, genomics and life science research. The Bioperl server provides an online resource for modules, scripts, and web links.
http://www.bioperl.org

The BioJava Project is an open-source project dedicated to providing Java tools for processing biological data.
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BioJava  Java framework for processing biological data. It include objects for manipulating sequences, file parsers, DAS client and server suport, access to BioSQL and Ensembl databases, and powerful analysis and statistical routines including a dynamic programming...
http://biojava.org/

The Biopython Project is an international association of developers of freely available Python tools for computational molecular biology.
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biopython.org Main page  About the biopython project The Biopython Project is an international association of developers of freely available Python tools for computational molecular biology. It is a distributed collaborative effort to develop Python libraries and applications which...
http://biopython.org/

A hierarchical database system for displaying genomic data (originally C. elegans), suitable also for displaying other scientific data.
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The Sanger Institute: AceDB Database  B is a genome database designed specifically for handling bioinformatic data flexibly. It includes tools designed to manipulate genomic data, but is increasingly also used for non-biological data. User docs Admin docs Developer docs Other...
http://www.acedb.org/

BioLisp.org is a public resource supporting scientists who use Lisp to develop intelligent applications in the biological sciences. We collect and disseminate Lisp biocomputing code, and gather pointers to Lisp and other Intelligent BioComputing methods.
http://www.biolisp.org

BiBiServ supports Internet-based collaborative research, software development and distance education in bioinformatics.
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 Tool section currently offers bioinformatics tools for a large variety of tasks: Genome Comparison Alignments Primer Design RNA Studio Evolutionary Relationships Others As some analyses can take a long time sometimes over several hours BiBiServ...
http://bibiserv.techfak.uni-bielefeld.de/

Code generator for writing dynamic programming programs.
http://www.sanger.ac.uk/Software/Dynamite/

OO Interface to AceDB
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AcePerl  It provides functionality for connecting to remote ACEDB databases, performing queries, fetching ACE objects, and updating databases. The programmer's API is compatible with the JADE Java API, and interoperable with the API used by BoulderIO....
http://stein.cshl.org/AcePerl/

Simple but powerful data exchange language, suitable for serializing biological data objects.
http://www.genome.wi.mit.edu/genome_software/other/boulder.html

The Bioconductor project produces an open source software framework that will assist biologists and statisticians working in bioinformatics, with primary emphasis on inference using DNA microarrays, built mostly using R.
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Welcome to Bioconductor bioconductor.org  Conductor is an open source and open development software project for the analysis and comprehension of genomic data. Sections HomeWhat is it?DownloadDocumentationpeoplePublications PROJECT NEWS 2005-10-07 Changes in BioC Devel, September 2005 2005-09-08 Changes in BioC...
http://www.bioconductor.org/

Tools that searches multiple biomedical databases from your desktop.
http://www.bioquery.org/

C++ framework for rapid software prototyping in molecular modeling.
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BALL Biochemical Algorithms Library The BALL Website  Prototyping can significantly reduce development times in the field of Computational Molecular Biology and Molecular Modeling. BALL (Biochemical Algorithms Library) is an application framework in C that has been specifically designed for this purpose. It...
http://www.bioinf.uni-sb.de/OK/BALL/

Analytical tools and SQL scripts that solve common problems in drug discovery.
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HTS Tools  Screening tools for the scientist interested in analyzing large datasets. The goal of this work is to get the science back into the hands of the scientists by providing some simplified solutions to some difficult...
http://www.htstools.com/

PAL library is a Java toolkit for determining evolutionary trends.
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The PAL Project  Java library for molecular evolution and phylogenetics Version 1.5 (January 15, 2004) The PAL project (http www.cebl.auckland.ac.nz/pal-project) is a collaborative effort dedicated to provide a high quality Java library for use in molecular evolution and...
http://www.cebl.auckland.ac.nz/pal-project/

Software development for structural bioinformatics. Runs on Unix, Windows and MacOSX.
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M o l T a l k computational environment in Structural Bioinformatics  Talk a computational environment for Structural Bioinformatics Download Documentation MolTalk is a computational environment for doing Structural Bioinformatics. It interprets PDB formatted files and creates an object representation of the structure-chain-residue-atom hierarchy. Through the use...
http://www.moltalk.org/